The aim of this project is to investigate and develop a silicon based microdosimeter which offers the possibility of replacing the current proportional gas counter for measurements of radiation deposited in cellular (10um diameter) sized volumes. Such a device will be more portable, easier to use and cheaper.
A prototype microdosimeter using Silicon-On-Insulator(SOI) technology was built at Fujitsu Research Laboratories Ltd. The device has been tested under clinical conditions in several high LET radiation oncology modalities including Boron Neutron Capture Therapy (BNL,USA and Kyoto, Japan), Fast Neutron Therapy (Harper Hospital, Detroit) and Fast Proton Therapy (KEK, Japan). Several of these devices will be tested in low earth orbit as part of the project, a collaborative project between CMRP, USNA, Johns Hopkins University and Memorial Sloan Kettering Cancer Care Centre.
Nanodosimetry aims to measure the spatial distribution of ionisations within a low pressure gas model of a DNA segment. This information may be used to predict the radiobiological propeties of the radiation field, with applications in proton and charged-particle therapy, radiation protection, and space research. This research is carried out in close collaboration with Loma Linda Proton Therapy Centre.
Microbeam Radiation Therapy (MRT) is a new kind of radiation treatment for cancer patients which uses a uniplanar array of synchrotron X-ray beams each 30 microns in thickness. CMRP has proposed and tested a new method of dose mapping for single 30 micron beams with a spatial resolution of 1 micron using vertical MOSFET detectors.
Collaborators: European Synschrotron Radiation Facility, Illawarra Cancer Care Centre, St. George Hospital (Australia), BNL(USA), REM OXFORD (UK)
We are studying the application of P-I-N silicon neutron dosimeters and MOSFETs for separate dosimetry in mixed gamma-neutron fields and verification of Monte-Carlo calculations in Boron Neutron Capture Therapy (BNCT), fast neutron therapy, Cf-252 brachytherapy, and proton therapy.
Monte Carlo Techniques
Monte Carlo techniques are used extensively in the simulation of experimental measurements. The group is involved with the use of such tools as: